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1 edition of Toxicology and Carcinogenesis Studies of T-Butyl Alcohol (Cas No. 75-65-0) in F344/N Rats and B6C3F1 Mice, Tech. Report Series, No. 436, U.S. Dept. of Health and Human Services, 1995. found in the catalog.

Toxicology and Carcinogenesis Studies of T-Butyl Alcohol (Cas No. 75-65-0) in F344/N Rats and B6C3F1 Mice, Tech. Report Series, No. 436, U.S. Dept. of Health and Human Services, 1995.

Toxicology and Carcinogenesis Studies of T-Butyl Alcohol (Cas No. 75-65-0) in F344/N Rats and B6C3F1 Mice, Tech. Report Series, No. 436, U.S. Dept. of Health and Human Services, 1995.

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Published .
Written in English


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ContributionsNational Cancer Institute (U.S.)
ID Numbers
Open LibraryOL17698250M

Abstract. Risk assessment is the process of determining the nature and extent of risks to human health and the environment. In a widely cited report, Risk Assessment in the Federal Government: Managing the Process (often referred to as the “Red Book”), risk assessments for human health are broadly defined as “the characterization of the potential adverse health effects of human exposures. Tert-butyl alcohol (TBA) is a clear, noncorrosive liquid. It is miscible with water as well as most common organic solvents and forms azeotrope. The sterically hindered tertiary butyl group imparts stability compare to primary and secondary alcohols. In result, the solubility and oxidative stability.

Read chapter 3. Insecticide Toxicology: Gulf War and Health, Volume 2, is the second in a series of congressionally-mandated studies by the Institute of M. Toxicological Review of tert-Butyl Alcohol 1 DISCLAIMER 2 This document is a preliminary draft for review purposes only. This information is 3 distributed solely for the purpose of pre-dissemination peer review under applicable information 4 quality guidelines.

2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a al formula: C₆H₁₄O₂. Toxicology and Carcinogenesis Studies of T-Butyl Alcohol (CAS No. ) in F/N Rats and B6C3F1 Mice (Drinking Water Studies) Exit Prepared by the U.S. Department of Health Service's National Toxicology Program, this Web page provides the abstract of a .


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Toxicology and Carcinogenesis Studies of T-Butyl Alcohol (Cas No. 75-65-0) in F344/N Rats and B6C3F1 Mice, Tech. Report Series, No. 436, U.S. Dept. of Health and Human Services, 1995 Download PDF EPUB FB2

T -Butyl alcohol is widely used in the manufacture of perfumes and a variety of cosmetics. It is also used as a raw material in the production of isobutylene, which may be used to produce methyl tertiary butyl ether, a common gasoline additive, or to produce butyl elastomers used in.

t-Butyl Alcohol, NTP TOX CONTRIBUTORS. This NTP report on the toxicity studies of. t-butyl alcohol is based primarily on day and week studies. that took place from August through June National Toxicology Program.

Evaluated experiment, interpreted results, and reported findings. Joel Mahler, D.V.M., Study Scientist. John.

toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether (cas no. ) in f/n rats and b6c3f. mice and a toxicology study of propylene glycol mono-t-butyl ether in male nbr rats (inhalation studies) national toxicology program p.o.

box research triangle park, nc march ntp tr nih File Size: 9MB. Toxicology and carcinogenesis studies of t-butyl alcohol (CAS no.

) in F/N rats and B6C3F₁ mice (drinking water studies) T-Butyl alcohol, NTP TR T-Butyl alcohol (drinking water studies) Responsibility: National Toxicology Program. Get this from a library. NTP technical report on the toxicology and carcinogenesis studies of t-butyl alcohol (CAS no.

) in F/N rats and B6C3F₁ mice. NTP (). Toxicology and carcinogenesis studies of t-butyl alcohol (CAS #75–65–0) in F/N rats and B6C3F 1 mice (drinking water studies). NTP TR National Toxicology Program, U.S. Department of Health and Human Services, Public Health Service, National Institutes of by: NTP.

Toxicology and Carcinogenesis Studies of t-Butyl Alcohol (CAS No. ) in F/N Rats and B6C3F1 Mice. National Toxicology Program, Technical Report No.National Institutes of Health, Public Health Service, U.S.

Department of Health and. NTP, in progress [a]. Toxicology and carcinogenesis studies of Propylene glycol mono-t-butyl ether (CAS No. ) in F/N rats and B6C3F1 mice and a toxicology study of propylene glycol mono-t-butyl ether in male NBR rats (Inhalation studies).

Draft Technical Report Series No. Cited by: 7. Toxicology and carcinogenesis studies of 26 t-butyl alcohol (CAS no ) in F/N rats and B6C3F1 mice (drinking water 27 studies) (pp. Research Triangle Park, NC.

28 30)NTP (National Toxicology Program). tert-Butyl alcohol (TBA), also called tert-butanol or t-butanol, is the simplest tertiary alcohol, with a formula of (CH 3) 3 COH (sometimes represented as t-BuOH).It is one of the four isomers of butanol. tert-Butyl alcohol is a colorless solid, which melts near room temperature and has a camphor-like is miscible with water, ethanol and diethyl etherBeilstein Reference: Toxicology and carcinogenesis studies of t-butyl alcohol (CAS no ) in F/N rats and B6C3F1 mice (Drinking water studies) Author: NTP () ().

(NTPTR). Research Triangle Park, NC: National Toxicology Program. HERO ID: Toxicological Review of. tert-Butyl Alcohol (tert-Butanol) (CAS No. ) In Support of Summary Information on the Integrated Risk Information System (IRIS) September This document is an.

Interagency Science Consultation Review draft. This information is. Ninety-day toxicity studies were conducted in B6C3F1 mice and Fischer (F) rats of both sexes using dosed water. Dose levels of t-butyl alcohol were 0, 1, 2, and 4% (w/v).

Lethality was observed at the 4% level of both sexes and by: Tert-butanol is a tertiary alcohol alcohol that is isobutane substituted by a hydroxy group at position 2.

It has a role as a human xenobiotic metabolite. It derives from a hydride of an isobutane. Tert-butyl alcohol is a colorless oily liquid with a sharp alcohol odor. Floats and mixes with water.

Produces irritating vapor. Author(s): National Toxicology Program (U.S.) Title(s): NTP technical report on the toxicology and carcinogenesis studies of t-butyl alcohol (CAS no. ) in F/N rats and B6C3F₁ mice (drinking water studies)/ National Toxicology Program.

NTP National Toxicology Program () Toxicology and Carcinogenesis Studies of t-Butyl Alcohol in F/N Rats and B6C3F1 Mice (Tech Rep Ser No ; NIH Publ No. ), Research Triangle Park, NC Google ScholarCited by: 2. Basis for original (SCP) IDLH: No data on acute inhalation toxicity are available on which to base the IDLH for tert-butyl alcohol, but Patty [] reported that the signs of intoxication on the part of animals exposed to its vapors are similar to those induced by the other butyl alcohols [Weese ].

For this draft technical standard. Toxicological Review of tert-Butyl Alcohol (tert-Butanol) (CAS No. ) April NOTICE. This document is a. Public Comment Draft. This information is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA.

Toxicology and Carcinogenesis Studies of t-Butyl Alcohol (CAS No. ) in F/N Rats and B6C3F Mice (Drinking Water Studies) Exit Prepared by the U.S.

Department of Health and Human Service's National Toxicology Program, this Web page provides information on the carcinogenicity of TBA; Remediation and Treatment. National Toxicology ProgramToxicology and carcinogenesis studies of tert-butyl alcohol in F/N rats and B6C3F1 mice (Tech.

Rep. Ser. ; NIH Publ. Cited by: 1. Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, was selected by the Awards Committee as the Society of Toxicologic Pathology Achievement Award recipient. Dr. Maronpot has significantly influenced the field of toxicologic pathology in many different ways, including as a leader, manager, educator, and author.

He is internationally recognized and highly respected for his scientific.NTP technical report on the toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether (CAS No.

) in F/N rats and B6C3F1 mice and a toxicology study of propylene.tertiary-Butyl Alcohol (TBA), a fuel oxygenate and breakdown by-product of Methyl tertiary Butyl Ether (MtBE), is a significant potential groundwater contaminant because of its mobility, recalcitrant nature, and potential toxicity.

Exposure to TBA can lead to irritation of mucous membranes, nausea, defatting of the skin, and intoxication. Metabolism of TBA leads to the formation of 2-methyl